What is Pancreatic Can.cer?
Pancreatic can.cer develops when the exocrine cells of the pancreas begin to multiply uncontrollably. One of the major challenges with this type of can.cer is that it often goes undetected in its early stages.
This is because noticeable symptoms typically do not appear until the disease has progressed and spread to other areas of the body.
A Difficult Diagnosis and Treatment Challenge
According to the American Can.cer Society, pancreatic can.cer is not only among the most commonly diagnosed can.cers but also one of the most aggressive and hardest to treat. It often shows resistance to conventional treatments like chemotherapy, making it a particularly daunting diagnosis.
Its anatomical position—tucked behind the stomach and surrounded by critical organs and major blood vessels—adds to the complexity of treatment.

These surrounding structures are easily affected, making surgery riskier. In addition, the pancreas has a low immune cell presence, which reduces the body’s natural defenses against can.cer progression.
Risk Factors and Influences
The National Can.cer Institute of the United States points out that both genetic predispositions and lifestyle habits can contribute to the development of pancreatic can.cer. Key risk factors include:
- Heavy tobacco use
- Obesity
- Diabetes
- Genetic syndromes, such as multiple endocrine neoplasia
- Certain hereditary conditions
In a conversation with the Peruvian radio station Radio Programas, oncologist Dr. Ramiro Fernández emphasized that people over the age of 65 are at greater risk. This is often due to cumulative lifestyle choices and underlying health conditions common in older adults.
Treatment Options and Considerations
Dr. Fernández noted that treatment strategies for pancreatic can.cer depend on several critical factors, including the tumor’s size, its location, and the extent of its spread to nearby organs.

Given that many of these organs are vital to survival, treatment plans must be carefully customized.
One of the biggest hurdles in managing this disease is that most patients are diagnosed at a late stage, making them poor candidates for surgery or other intensive procedures.
Many simply cannot endure aggressive treatments due to the advanced progression of the can.cer.
The Importance of Early Detection
Recognizing the early signs of pancreatic can.cer is key to improving survival rates. Dr. Fernández highlights several warning symptoms that should not be ignored:
- Unexplained weight loss
- Jaundice (yellowing of the skin or eyes)
- Persistent back pain
- Dark-colored urine
- Chronic fatigue
- Ongoing abdominal discomfort

If any of these symptoms arise, he strongly advises seeking medical attention promptly. Timely consultation with a healthcare provider can lead to an earlier diagnosis and a better chance of finding an effective treatment approach, ultimately helping to reduce the disease’s high mortality rate.